Clinical Significance of Tumor Regression Grade in Rectal Cancer with Preoperative Chemoradiotherapy
نویسندگان
چکیده
منابع مشابه
Clinical Significance of Tumor Regression Grade in Rectal Cancer with Preoperative Chemoradiotherapy
PURPOSE Neoadjuvant chemoradiotherapy applied to the locally advanced rectal cancer reduces local recurrence and improves survival. We assessed tumor regression grade (TRG) and its influence on survival in rectal cancer patients treated with chemoradiotherapy followed by surgical resection. METHODS We studied 108 patients that were seen at our hospital between August 2004 and December 2008. P...
متن کاملPrognostic Significance of Tumor Regression Grade after Preoperative Chemoradiotherapy for Rectal Cancer
PURPOSE We assessed the impact of tumor regression grading (TRG) and its value in correlation to established prognostic factors in a cohort of rectal carcinoma patients treated by preoperative chemoradiotherapy (CRT). PATIENTS AND METHODS TRG was evaluated on surgical specimens of 385 patients treated within the preoperative CRT arm of the CAO/ARO/AIO-94 trial: 50.4 Gy was delivered, fluorour...
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BACKGROUND Complete tumor regression after preoperative chemoradiotherapy for rectal cancer has been associated with better disease-free and overall survival. The survival experience for patients with partial tumor regression is less clear. OBJECTIVE The aim of this meta-analysis was to evaluate the prognostic significance of partial response after preoperative chemotherapy on disease-free su...
متن کاملCorrelation between tumor regression grade and rectal volume in neoadjuvant concurrent chemoradiotherapy for rectal cancer
PURPOSE To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. MATERIALS AND METHODS We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume w...
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CD133 has been identified as a putative cancer stem cell (CSC) marker in various cancers including colorectal cancer. The relation between CD133 expression and biological characteristics of colorectal cancer remains to be clarified. Protein expression of CD133 was immunohistochemically evaluated in surgical specimens of 225 patients with colorectal cancer who were treated by surgery, as well as...
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ژورنال
عنوان ژورنال: Journal of the Korean Society of Coloproctology
سال: 2010
ISSN: 2093-7822
DOI: 10.3393/jksc.2010.26.4.279